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Marta Madaghiele, PhD


Marta Madaghiele was born in 1978 in Maglie, Lecce, Italy. In 2003 she obtained her Master Degree in Materials Engineering, summa cum laude, from the University of Lecce. In 2004 she started her Ph.D. Program in Materials Engineering at the Department of Engineering for Innovation, University of Lecce, focusing her activities on the development of novel porous scaffolds for tissue engineering. As a sidework, she worked on the synthesis of biocompatible hydrogels for several biomedical applications. As part of her Doctoral Research Program, in 2005 she joined the VA Tissue Engineering Laboratories of the VA Boston HealthCare System, in Boston, MA, USA, to work on the design of collagen-based scaffolds for spinal cord regeneration in an animal model, collaborating also with the Fibers and Polymers Lab at the Department of Mechanical Engineering of the Massachusetts Institute of Technology, Cambridge, MA, USA.
In 2006 she returned to Italy to complete her Doctoral Program. As a post-doc fellow, she is currently collaborating with the Department of Engineering for Innovation of the University of Salento (formerly University of Lecce), with regard to the development of biodegradable polymeric devices, e.g. microspheres and/or hydrogels, for the controlled release of bioactive molecules.




  1. Sannino A, Madaghiele M, Conversano F, Mele G, Maffezzoli A, Netti PA. "Cellulose derivative-hyaluronic acid-based microporous hydrogels crosslinked through divynil sulfone (DVS) to modulate equilibrium sorption capacity and network stability". Biomacromolecules 5: 92-96, 2004. - Abstract
  2. Sannino A, Pappadà S, Madaghiele M, Maffezzoli A, Ambrosio L, Nicolais L. "Crosslinking of cellulose derivatives and hyaluronic acid with water-soluble carbodiimide". Polymer 46: 11206-11212, 2005. - Abstract
  3. Sannino A, Netti PA, Madaghiele M, Coccoli V, Luciani A, Maffezzoli A, Nicolais L. "Synthesis and characterization of macroporous poly(ethylene glycol)-based hydrogels for tissue engineering application". J Biomed Mater Res 79A: 229-236, 2006. - Abstract
  4. Sannino A, Madaghiele M, Lionetto MG, Schettino T, Maffezzoli A. "A cellulose-based hydrogel as a potential bulking agent for hypocaloric diets: an in vitro biocompatibility study on rat intestine". J Appl Polym Sci 102: 1524-1530, 2006. - Abstract
  5. Madaghiele M, Sannino A, Yannas IV, Spector M. "Collagen-based matrices with axially oriented pores." J Biomed Mater Res A. Published online September 26, 2007. - Abstract
  6. Sannino A, Madaghiele M. "Tuning the porosity of collagen-based scaffolds for use as nerve regenerative templates." J Cell Plast 45(2): 137-155, 2009. (Proceedings of Biofoams 2007) - Abstract
  7. Sannino A, Demitri C, Madaghiele M. "Biodegradable cellulose-based hydrogels: design and applications. " Materials 2(2): 353-373, 2009. - Abstract
  8. Madaghiele M, Piccinno A, Saponaro M, Maffezzoli A, Sannino A. "Collagen- and gelatine-based films sealing vascular prostheses: evaluation of the degree of crosslinking for optimal blood impermeability." J Mater Sci Mater Med, Epub May 18, 2009. - Abstract
  9. Sannino A, Madaghiele M, Demitri C, Scalera F, Esposito A, Esposito V, Maffezzoli A. "Development and characterization of cellulose-based hydrogels for use as dietary bulking agents." Accepted for publication on J Appl Polym Sci. - Abstract


Book Chapters

  1. Sannino A, Madaghiele M, Ambrosio L. "Biocompatibility and other properties of hydrogels in regenerative medicine’, in ‘Cellular response to Biomaterials", edited by L. Di Silvio, Woodhead Publishing Limited, Abington Hall, Abington, Cambridge, CB21 6AH, England (January 2009)


University of Salento   Facoltà di Ingengeria   Department of Engineering for Innovation
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